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We and changed the fresh breakdown “a keen estimator away from choices” toward “Ka while the an estimator regarding evolutionary price”
Authors’ response
I added a few dialogue activities in regards to the good reason why Ka thinking regarding several actions yield a lot more uniform abilities than just Ks opinions.
Brand new article writers next proceed to compare the outcome gotten for the various animals, and they infer ancestry-certain accelerations oriented solely towards the pairwise “human-other varieties” reviews. It doesn’t make sense. The new writers should be aware that we now have tricks for brand new estimate out of part-specific Ka, Ks and you will Ka/Ks percentages which use a multiple-variety sequence positioning which look at the fundamental phylogeny (come across particularly PAML – probably the most frequently made use of – Z. ادامه خواندن